Related Experiment Video
Updated: Jan 3, 2026

06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.7K
An elderly man with progressive focal nodular hyperplasia.
Koichi Hamada1,2, Satoshi Saitoh3, Noriyuki Nishino4
1Department of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, 1 Hikariga-oka, Fukushima-shi, Fukushima, 960-1295, Japan. koichi.hamada@mt.strins.or.jp.
Clinical Journal of Gastroenterology
|November 27, 2019
Summary
This study reports a rare case of focal nodular hyperplasia (FNH) in an elderly man, a condition typically seen in younger women. The patient
Area of Science:
- Hepatology
- Gastroenterology
- Radiology
Background:
- Focal nodular hyperplasia (FNH) is a benign liver lesion characterized by hepatocellular nodules.
- FNH predominantly affects young women, with rare occurrences in other demographics.
Observation:
- A 69-year-old man, post-renal pelvis carcinoma surgery, had no liver masses on initial surveillance CT scans.
- Ten years later, contrast-enhanced computed tomography (CECT) identified a hepatic mass, with subsequent MRI suggesting FNH.
Findings:
- The patient presented with a rare case of FNH in an elderly male.
- The FNH nodules demonstrated an increase in both number and size over time during follow-up.
Implications:
- This case expands the known demographic profile for FNH.
- Highlights the importance of vigilant surveillance for hepatic lesions, even in atypical patient populations.
- Suggests potential for nodular growth in FNH, warranting further investigation in elderly males.
Related Concept Videos
Menopause
3.5K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
3.5K
Tumor Progression
7.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.2K
Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
The Effect of Aging on Tissues
3.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.1K
