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Targeted therapy in oncology patients and skin: Pharmaceutical and dermocosmetic management
Athanasia Varvaresou1, Kriton Iakovou2, Fotini Mellou1
1Research Laboratory of Chemisty, Biochemistry and Cosmetic Science, Department of Biomedical Sciences, University of West Attica, Egaleo, Greece.
Background:
Numerous oncology patients who receive targeted therapy suffer from the skin adverse effects induced. Novel agents, that is tyrosine kinase inhibitors and RAS-RAF-MEK-ERK pathway, have given good results in patient survival while decreasing the systemic toxicities in comparison to conventional cytotoxic chemotherapy, but are also related to skin adverse effects.
Aims:
In this article, we highlighted the importance of specific pharmaceutical and dermocosmetic management of the untoward events of targeted therapy.
Conclusion:
The combination of Oncodermatology, Psychodermatology, Cosmetic Dermatology, Cosmetic Science, Dermatopharmacology and Aesthetic Science can offer a lot for the prevention or early relief of the cutaneous adverse effects in oncology patients receiving targeted therapy.
Insights
Targeted cancer therapies improve survival but cause skin issues. Combining oncodermatology and cosmetic science can prevent or relieve these side effects for better patient outcomes.
Area of Science:
- Oncology
- Dermatology
- Pharmacology
- Cosmetic Science
Background:
- Targeted cancer therapies, including tyrosine kinase inhibitors and RAS-RAF-MEK-ERK pathway agents, improve patient survival.
- These novel agents reduce systemic toxicities compared to traditional chemotherapy.
- However, targeted therapies frequently induce cutaneous adverse effects.
Purpose of the Study:
- To emphasize the significance of specialized pharmaceutical and dermocosmetic management strategies.
- To address the untoward skin events associated with targeted cancer therapy.
Main Methods:
- Review and synthesis of current knowledge on managing skin adverse effects from targeted therapy.
- Integration of principles from Oncodermatology, Psychodermatology, Cosmetic Dermatology, Cosmetic Science, Dermatopharmacology, and Aesthetic Science.
Main Results:
- Specific pharmaceutical interventions can mitigate treatment-induced skin toxicities.
- Dermocosmetic approaches offer supportive care and symptom relief.
- A multidisciplinary approach is crucial for comprehensive management.
Conclusions:
- The integration of Oncodermatology, Psychodermatology, Cosmetic Dermatology, Cosmetic Science, Dermatopharmacology, and Aesthetic Science is vital.
- This combined approach can significantly aid in the prevention and early management of cutaneous adverse effects.
- Improved patient quality of life is achievable through proactive and integrated dermatological care during targeted cancer therapy.
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