Related Experiment Video
Updated: Jan 3, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
Comparing methods for comparing networks
Mattia Tantardini1, Francesca Ieva2,3, Lucia Tajoli4
1Moxoff SpA, via Schiaffino 11/A, 20158, Milano, Italy.
Abstract:
With the impressive growth of available data and the flexibility of network modelling, the problem of devising effective quantitative methods for the comparison of networks arises. Plenty of such methods have been designed to accomplish this task: most of them deal with undirected and unweighted networks only, but a few are capable of handling directed and/or weighted networks too, thus properly exploiting richer information. In this work, we contribute to the effort of comparing the different methods for comparing networks and providing a guide for the selection of an appropriate one. First, we review and classify a collection of network comparison methods, highlighting the criteria they are based on and their advantages and drawbacks. The set includes methods requiring known node-correspondence, such as DeltaCon and Cut Distance, as well as methods not requiring a priori known node-correspondence, such as alignment-based, graphlet-based, and spectral methods, and the recently proposed Portrait Divergence and NetLSD. We test the above methods on synthetic networks and we assess their usability and the meaningfulness of the results they provide. Finally, we apply the methods to two real-world datasets, the European Air Transportation Network and the FAO Trade Network, in order to discuss the results that can be drawn from this type of analysis.
Related Concept Videos
Equivalent Resistance
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Comparing the Survival Analysis of Two or More Groups
Evolutionary Relationships through Genome Comparisons
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks

