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Vancomycin Infusion Methods on Phlebitis Prevention in Children

Maryam Tork-Torabi1, Mahboubeh Namnabati2, Zahra Allameh3

  • 1Student Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

Iranian Journal of Nursing and Midwifery Research
|November 28, 2019
PubMed

Insights

A new vancomycin infusion method significantly reduced phlebitis in hospitalized children. This intervention proved more effective than routine methods in preventing intravenous line inflammation.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Pharmacy
  • Nursing Care

Background:

  • Hospitalized children frequently require antibiotic therapy, with vancomycin being commonly prescribed.
  • Phlebitis, inflammation of the vein, is a prevalent side effect of intravenous injections, particularly with vancomycin.
  • The study addresses the need for effective phlebitis prevention strategies in pediatric vancomycin therapy.

Purpose of the Study:

  • To compare the efficacy of an intervention vancomycin infusion method versus routine methods in preventing phlebitis in hospitalized children.
  • To evaluate the impact of specific phlebitis prevention guidelines on intravenous catheter complications.

Main Methods:

  • A quasi-experimental study involving 74 children (1 month to 6 years) receiving vancomycin.
  • Two groups were established: a control group (37 children) receiving routine infusion and an intervention group (37 children) using author-developed phlebitis prevention guidelines.
  • Data were analyzed using SPSS, with statistical significance set at p < 0.05.

Main Results:

  • Phlebitis occurred in 45.90% of the intervention group compared to 89.10% in the control group.
  • The frequency of phlebitis was significantly lower in the intervention group (χ²= 15.79, p < 0.001).
  • The average time to phlebitis onset was significantly longer in the intervention group (t=2.99, p = 0.004).

Conclusions:

  • The intervention vancomycin infusion method is significantly more effective in reducing phlebitis associated with intravenous catheters in children.
  • Implementing specific phlebitis prevention guidelines can improve patient outcomes and reduce complications during vancomycin therapy.
Abstract

Keywords:
Hospitalized childIranintravenous infusionphlebitisvancomycin

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