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Updated: Jan 3, 2026
Simultaneous Measurement of Mitochondrial Calcium and Mitochondrial Membrane Potential in Live Cells by Fluorescent Microscopy
Published on: January 24, 2017
Fluorescence Imaging of Mitochondria with Three Different Sets of Signals Based on Fluorene Cation Fluorescent Probe
Weishan Wang1, Yong Liu1, Jie Niu1
1Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, People's Republic of China.
Abstract:
Herein, we develop a novel mitochondria-targetable fluorescence probe (FVPI) based on fluorene cation derivative. This mitochondria-targetable fluorescence probe exhibits large Stokes shift in various solutions. In addition, FVPI displays numerous advantages, including high photostability, low cytotoxicity, and two-photon properties. View of the above features, FVPI is successfully capable of imaging mitochondria in biological systems with three different sets of signals. This finding will provide a new platform for the constructing mitochondria-targetable fluorescent probes with excellent optical properties.
