Splenic rupture as a cause of sudden death in undiagnosed chronic myelogenous leukemia
Related Experiment Videos
B R Nestok1, J D Goldstein, P Lipkovic
1Department of Pathology, University of Florida College of Medicine, Jacksonville 32209.
The American Journal of Forensic Medicine and Pathology
|September 1, 1988
Abstract:
A 35-year-old man died suddenly in a clinic waiting area after repeated visits for flu-like symptoms. At autopsy, hemoperitoneum, splenic capsular rupture, and splenomegaly were found. Microscopic examination, special stains, and immunoperoxidase studies revealed findings consistent with chronic myelogenous leukemia. Spontaneous splenic rupture is an unusual presenting feature of chronic myelogenous leukemia. The symptoms of leukemia may mimic those of other "benign" disorders and misdiagnosis may lead to catastrophic consequences in some instances.