Dental development in children born to Zikv-infected mothers: a case-based study
Mabel Cristina Paiva Machado da Silva1, Manuela de Andrade Arnaud1, Maria Carlla Aroucha Lyra1
1University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Camaragibe, Pernambuco, Brazil.
Background:
In Brazil, in October 2015, an outbreak of Zika virus (ZIKV) infection and an increase in newborns with microcephaly suggested a relationship between maternal infection and microcephaly in children.
Objective:
First, to assess the presence of dental bud sin 13 infants with a confirmed diagnosis of congenital ZIKV syndrome, born to mothers infected with the virus during pregnancy; second, to evaluate the dental development of these children at a 36-month follow-up.
Design:
Case-based longitudinal study.
Results:
Dental radiographs in the first semester showed that all children had dental buds. Along with the study, the individuals presented with various dental disturbances. At the end of the evaluation period, some children still had incomplete deciduous dentition.
Conclusion:
The abnormal chronology of dental eruption and dental development disturbances in children with microcephaly infected with ZIKV born to infected mothers indicate a possible role of the virus in odontogenesis.
More Related Videos
Related Concept Videos
01:15Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
01:10Zygotic Development And Stem Cell Formation