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Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition
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Snus: a compelling harm reduction alternative to cigarettes.

Elizabeth Clarke1, Keith Thompson2, Sarah Weaver3

  • 1Imperial Brands Plc, 121 Winterstoke Road, Bristol, BS3 2LL, UK. Elizabeth.Clarke@uk.imptob.com.

Harm Reduction Journal
|November 29, 2019
PubMed
Summary
This summary is machine-generated.

Snus, an oral tobacco product, shows significantly lower health risks than smoking. While not linked to major cancers or cardiovascular issues, high consumption may affect diabetes risk, and it can cause reversible oral lesions.

Keywords:
Cigarette smokingEpidemiologyHarm reductionHealth effectsPublic healthSnusTobacco

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Area of Science:

  • Tobacco harm reduction
  • Public health
  • Oral medicine

Background:

  • Snus is a Swedish oral smokeless tobacco product.
  • Its health effects and harm reduction potential compared to cigarettes require examination.

Purpose of the Study:

  • To review snus use effects on lung cancer, cardiovascular disease, pancreatic cancer, diabetes, oral cancer, and oral disease.
  • To assess snus's harm reduction potential as a cigarette alternative.

Main Methods:

  • Literature review of scientific studies on snus use and health outcomes.
  • Comparison of snus and cigarette prevalence and disease incidence across EU countries.

Main Results:

  • Snus use is not a significant risk factor for lung, cardiovascular, pancreatic, or oral cancers.
  • High snus consumption may be linked to increased diabetes risk, but results are inconclusive.
  • Snus use is associated with reversible oral lesions.
  • Sweden, with high snus use, has the lowest EU cigarette smoking prevalence and lowest tobacco-related mortality and male lung cancer incidence.

Conclusions:

  • Snus use offers significant harm reduction benefits compared to cigarette smoking.
  • The health risks of snus are considerably lower than those of smoking, reflected in lower disease rates in Sweden.