Related Experiment Video

Updated: Jan 3, 2026

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.2K

Modelling the neonatal system: A joint analysis of length of stay and patient pathways

Shola Adeyemi1, Eren Demir2

  • 1Statsxperts Consulting Ltd, Haverhill, UK.

The International Journal of Health Planning and Management
|November 29, 2019
PubMed

Insights

One in seven UK babies need neonatal care, straining services. This study reveals a strong link between a baby's care pathway and their total length of stay (LoS), highlighting the need for improved discharge policies.

Area of Science:

  • Neonatal care
  • Health services research
  • Statistical modeling

Background:

  • Increasing demand for neonatal care in the UK strains resources.
  • Budgetary constraints and lack of investment impact neonatal unit performance.
  • Existing models do not jointly analyze length of stay (LoS) and patient pathways.

Purpose of the Study:

  • To examine the association between neonatal care pathways and length of stay (LoS).
  • To develop a novel statistical approach for analyzing longitudinal outcomes in neonatal care.
  • To inform discharge policies and improve neonatal service performance.

Main Methods:

  • Utilized generalized linear mixed modeling, extended for multiple outcomes.
  • Analyzed data from 1002 neonates to investigate the relationship between care pathways and LoS.
  • Developed a novel statistical approach to assess evolving associations over time.

Main Results:

  • Identified a high positive association between a neonate's pathway and total LoS.
  • Demonstrated the utility of a joint analysis of LoS and care pathways.
  • The developed statistical approach can be applied to other long-term care scenarios.

Conclusions:

  • Neonatal care pathways significantly influence total length of stay.
  • Discharge policies require careful review to optimize LoS and resource utilization.
  • The novel statistical methodology offers broader applications in chronic disease management.

Keywords:
joint analysislength of stayneonatal carepatient-level modelling

More Related Videos

Trajectory Data Analyses for Pedestrian Space-time Activity Study16:14

Trajectory Data Analyses for Pedestrian Space-time Activity Study

Published on: February 25, 2013

14.0K

Related Concept Videos

Noncompartmental Analysis: Mean Residence Time01:05

Noncompartmental Analysis: Mean Residence Time

According to statistical moment theory, mean residence time (MRT) is an important measure in pharmacokinetics. MRT can be defined as the expected mean of a probability density function distribution. It provides valuable insights into drug disposition in the body.
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
518
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis00:59

Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis

Noncompartmental analyses offer an alternative method for describing drug pharmacokinetics without relying on a specific compartmental model. In this approach, the drug's pharmacokinetics are assumed to be linear, with the terminal phase log-linear. This assumption allows for simplified analysis and interpretation of the drug's behavior in the body.
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
276
Multicompartment Models: Overview01:14

Multicompartment Models: Overview

Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
462
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
821
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
211
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
487