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Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer
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Label-Free Detection of Transferrin Receptor by a Designed Ligand-Protein Sensor
Wanshan Liu1, Shiyu Sun1, Yida Huang1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, P. R. China.
Chemistry, an Asian Journal
|November 29, 2019
Abstract:
Advanced detection of biomarkers in biofluids plays an important role in disease diagnosis and prognosis. Current techniques with pre-labelling suffer from high cost and complicated operation, etc. Herein, we designed a label-free electrochemical biosensor for rapid detection of transferrin receptor with desirable linear range, sensitivity, specificity, reproducibility, and stability for practical applications.

