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Updated: Jan 3, 2026

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
Sclerotherapy as an esthetic indication in oral vascular malformations: a case series
Brena Rodrigues Manzano1, Aloizio Maciel Premoli1, Natalia Garcia Santaella1
1Department of Surgery, Stomatology, Pathology, and Radiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo, Bauru, SP, Brazil.
Background:
The use of monoethanolamine oleate 5% is effective for the treatment of vascular malformations with low blood flow.
Objectives:
To report a case series of vascular malformations in the mouth and oral cavity treated with monoethanolamine oleate 5%.
Methods:
A retrospective descriptive study was performed in electronic patient charts covering seven years. Patient demographics, diagnostic resources, lesion site, size, and number of applications of monoethanolamine oleate 5% were collected.
Results:
A total of 21 vascular malformations were recorded, located mostly on the lower lip (52.3%) and resolved in a single application in 14 patients. The authors found 19 patients treated with sclerotherapy. Thirteen were women and six were men, with a mean age of 61 years.
Study Limitation:
Small sample size.
Conclusions:
Sclerotherapy is an effective treatment for vascular malformations of the lips and oral cavity, with resolution after only one or two applications (n=16).
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