Isolation of Malassezia spp. in HIV-positive patients with and without seborrheic dermatitis
Related Experiment Video
Updated: Sep 20, 2026
Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals
Published on: January 5, 2016
Gabriela Moreno-Coutiño1, Carlos D Sánchez-Cárdenas2, Yesenia Bello-Hernández2
1Mycology Department, Dr. Manuel Gea González General Hospital, Delegación Tlalpan, Mexico City, Mexico.
Background:
Malassezia, a skin saprophyte, is frequently isolated from patients with seborrheic dermatitis, which is one of the most common dermatoses in HIV-infected patients. Its role in pathophysiology has not been defined.
Objective:
To determine whether patients living with HIV and seborrheic dermatitis have more Malassezia than those without seborrheic dermatitis.
Method:
This is an descriptive, observational, prospective cross-sectional study to which all adult patients living with HIV that attend the infectious disease outpatient clinic at the Dr. Manuel Gea González General Hospital were invited. Patients presenting with scale and erythema were included in Group 1, while patients without erythema were included in Group 2. Samples were taken from all patients for smear and culture.
Results:
Thirty patients were included in each group. All patients with seborrheic dermatitis had a positive smear, with varying amounts of yeasts. In the control group, 36.7% of patients had a negative smear. The results are statistically significant, as well as the number of colonies in the cultures. Study limitations The study used a small sample size and the subspecies were not identified.
Conclusions:
Patients with clinical manifestations of seborrheic dermatitis have larger amounts of Malassezia. Further studies need to be performed to analyze if the greater amount is related to imbalances in the microbiota of the skin.
