Related Experiment Video
Updated: Jan 3, 2026

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
Published on: October 17, 2018
Evaluation of functional disability after Chikungunya infection
Cristiane Silvia Panato1, Eduardo Durans Figueredo1, Daniela Bassi1
1Universidade CEUMA, Programa de Pós-Graduação em Gestão de Programas e Serviços de Saúde, São Luís, MA, Brasil.
Introduction:
Chikungunya (CHIK) is caused by the Chikungunya virus, which is an Alphavirus of the Family Togaviridae transmitted to humans through female mosquitoes of the genus Aedes.
Methods:
A cross-sectional study was conducted involving the administration of a questionnaire addressing sociodemographic and health variables and the Roland-Morris Disability Questionnaire on general pain to patients with CHIK in the City of Imperatriz, Brazil, between January and December 2017.
Results:
Data of a total of 130 patients were evaluated. The mean age was 52 years (standard deviation=13.3); majority of the patients were female (n=120) with a prevalence of 38.0% for functional disability. Statistical differences were noted for marital status (p=0.037), presence/absence of comorbidities (p=0.050), and the use of medications prior to the diagnosis of CHIK (p=0.050), use of methotrexate (p=0.030), use of nonsteroidal anti-inflammatory drugs (p≤0.035), and use of nonhormonal anti-inflammatory drugs (p=0.001).
Conclusions:
Patients in the chronic phase of CHIK present functional disability, thus alerting healthcare professionals to the importance of implementing actions aimed at an adequate treatment in all phases of the disease, mainly related to pain treatment and motor rehabilitation.

