Related Experiment Video

Updated: Jan 3, 2026

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
06:24

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

15.6K

The characteristics of acute necrotizing pancreatitis in different age stages: An MRI study

Dan Dan Yang1, Hou Dong Zuo1, Chang Qiang Wu2

  • 1Sichuan Key Laboratory of Medical Imaging and Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Wenhua Road 63, Nanchong 637099, Sichuan, PR China.

European Journal of Radiology
|November 29, 2019
PubMed
Abstract

Insights

Acute necrotizing pancreatitis (ANP) prevalence and characteristics vary by age. Elderly patients show higher ANP rates and more extensive extrapancreatic necrosis, impacting clinical outcomes.

Area of Science:

  • Radiology
  • Gastroenterology
  • Medical Imaging

Background:

  • Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis.
  • Understanding ANP characteristics across different age groups is crucial for predicting outcomes.

Purpose of the Study:

  • To investigate the age-specific characteristics of acute necrotizing pancreatitis (ANP) using magnetic resonance imaging (MRI).
  • To correlate ANP subtypes and extent with clinical outcomes in different age demographics.

Main Methods:

  • Retrospective review of MRI scans from 716 acute pancreatitis patients.
  • Classification of ANP into extrapancreatic necrosis (EPN) alone, pancreatic necrosis (PN) alone, and combined necrosis.
  • Quantification of necrosis extent and comparison across young, middle-aged, and elderly groups.

Main Results:

  • ANP was identified in 18% of patients, with highest prevalence in the elderly (28.9%).
  • Elderly and middle-aged patients had higher rates of combined necrosis.
  • Elderly patients showed more extensive extrapancreatic involvement than younger patients.

Conclusions:

  • ANP subtypes and their extent significantly correlate with clinical outcomes.
  • Age is a critical factor influencing ANP development and presentation.
  • Tailoring treatment strategies based on age and ANP characteristics is essential.
Keywords:
Acute necrotizing pancreatitisAge factorMagnetic resonance imagingNecrosis

More Related Videos

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

18.6K
Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection07:38

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection

Published on: May 10, 2024

1.1K

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
665
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.9K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.1K