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Unmet needs in the management of cardiovascular risk in inflammatory joint diseases

Santos Castañeda1,2, Esther F Vicente-Rabaneda1, Noelia García-Castañeda1

  • 1Rheumatology Division, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain.

Expert Review of Clinical Immunology
|November 30, 2019
PubMed

Insights

Cardiovascular disease risk is elevated in inflammatory joint diseases (IJDs). Early CV risk identification and management, alongside IJD control, are crucial for better patient outcomes.

Area of Science:

  • Rheumatology
  • Cardiology
  • Internal Medicine

Background:

  • Inflammatory joint diseases (IJDs) like rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis are linked to increased cardiovascular (CV) morbidity and mortality.
  • Established management strategies for CV disease in IJD patients are lacking.

Purpose of the Study:

  • To summarize epidemiologic, pathophysiological, and clinical risk factors for CV disease in IJDs.
  • To discuss early diagnosis and risk stratification of CV disease in these patients.
  • To provide expert opinion on managing CV risk in IJD.

Main Methods:

  • Review of epidemiologic, pathophysiological, and clinical data.
  • Discussion of diagnostic and risk stratification methods.
  • Synthesis of expert opinion on management strategies.

Main Results:

  • The modified SCORE index, based on EULAR 2017 recommendations, is a common European risk algorithm for IJD patients.
  • Early CV risk identification using noninvasive imaging and multidisciplinary approaches is essential.
  • Managing the underlying IJD and controlling CV risk factors are critical.

Conclusions:

  • Early identification and comprehensive management of CV disease risk factors are vital for patients with IJDs.
  • A multidisciplinary approach focusing on heart-healthy habits and IJD control is recommended.
  • Non-steroidal anti-inflammatory drugs may offer a different risk-benefit profile in IJDs compared to the general population.

Keywords:
Ankylosing spondylitiscardiovascular diseasecardiovascular risk factorsinflammatory joint diseasespreventionpsoriatic arthritisrheumatoid arthritis

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