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Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
Improvement in Pediatric Cardiac Surgical Outcomes Through Interhospital Collaboration
Michael Gaies1, Sara K Pasquali1, Mousumi Banerjee2
1Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan.
Insights
Pediatric Cardiac Critical Care Consortium (PC4) participation improved pediatric cardiac surgery outcomes, reducing mortality and complications. These improvements were not seen in non-participating hospitals, highlighting PC4
Area of Science:
- Pediatric Cardiac Surgery
- Healthcare Quality Improvement
- Clinical Registries
Background:
- Complex pediatric cardiac surgery carries significant risks.
- Outcomes vary widely across healthcare facilities.
- The Pediatric Cardiac Critical Care Consortium (PC4) was established to enhance care quality through data sharing and collaboration.
Purpose of the Study:
- To evaluate if patient outcomes improved over time within the PC4 initiative.
- To assess the impact of PC4 participation on pediatric cardiac surgical outcomes.
Main Methods:
- Analysis of 19,600 hospitalizations from 18 hospitals in the PC4 registry (August 2014-June 2018).
- Comparison of outcomes between the initial 2 years of PC4 participation (baseline) and subsequent periods.
- Evaluation of outcomes in a cohort of similar non-PC4 hospitals during the same era.
Main Results:
- Significant reductions observed post-PC4 participation: intensive care unit mortality (22% RR), in-hospital mortality (24% RR), major complications (12% RR), ICU length of stay (5% RR), and ventilation duration (13% RR).
- No significant improvements in mortality or complications were noted in non-PC4 hospitals.
- Baseline period showed no evidence of improvement prior to the 2-year exposure.
Conclusions:
- Hospitals participating in PC4 demonstrated improved pediatric cardiac surgical outcomes.
- Improvements are likely attributable to PC4's collaborative learning and data transparency.
- Observed improvements were independent of general trends in healthcare quality.
Background:
Patients undergoing complex pediatric cardiac surgery remain at considerable risk of mortality and morbidity, and variation in outcomes exists across hospitals. The Pediatric Cardiac Critical Care Consortium (PC4) was formed to improve the quality of care for these patients through transparent data sharing and collaborative learning between participants.
Objectives:
The purpose of this study was to determine whether outcomes improved over time within PC4.
Methods:
The study analyzed 19,600 hospitalizations (18 hospitals) in the PC4 clinical registry that included cardiovascular surgery from August 2014 to June 2018. The primary exposure was 2 years of PC4 participation; this provided adequate time for hospitals to accrue data and engage in collaborative learning. Aggregate case mix-adjusted outcomes were compared between the first 2 years of participation (baseline) and all months post-exposure. We also evaluated outcomes from the same era in a cohort of similar, non-PC4 hospitals.
Results:
During the baseline period, there was no evidence of improvement. We observed significant improvement in the post-exposure period versus baseline for post-operative intensive care unit mortality (2.1% vs. 2.7%; 22% relative reduction [RR]; p = 0.001), in-hospital mortality (2.5% vs. 3.3%; 24% RR; p = 0.001), major complications (10.1% vs. 11.5%; 12% RR; p < 0.001), intensive care unit length of stay (7.3 days vs. 7.7 days; 5% RR; p < 0.001), and duration of ventilation (61.3 h vs. 70.6 h; 13% RR; p = 0.01). Non-PC4 hospitals showed no significant improvement in mortality, complications, or hospital length of stay.
Conclusions:
This analysis demonstrates improving cardiac surgical outcomes at children's hospitals participating in PC4. This change appears unrelated to secular improvement trends, and likely reflects PC4's commitment to transparency and collaboration.
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