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Genetic and Metabolic Conditions

Lawrence M Stankovits1, Alexander H Lopyan2

  • 1Pediatric Orthopedic Surgery, Monmouth Medical Center, Long Branch, NJ, USA.

Pediatric Clinics of North America
|November 30, 2019
PubMed

Insights

Genetic and metabolic disorders frequently cause orthopedic issues in children. This review highlights common conditions and treatment challenges for pediatric orthopedic practitioners.

Area of Science:

  • Orthopedics
  • Genetics
  • Metabolic Disorders

Background:

  • Genetic and metabolic conditions often manifest with significant orthopedic complications.
  • Pediatric orthopedic practices encounter a diverse range of these complex cases.

Purpose of the Study:

  • To review common orthopedic manifestations of genetic and metabolic diseases in pediatric patients.
  • To provide practical insights for managing these challenging pediatric cases.

Main Methods:

  • Literature review of common orthopedic conditions associated with genetic and metabolic disorders.
  • Synthesis of clinical pearls and potential pitfalls in pediatric orthopedic practice.

Main Results:

  • Identification of prevalent orthopedic manifestations across various genetic and metabolic syndromes.
  • Discussion of specific challenges and management strategies for affected children.

Conclusions:

  • Accurate diagnosis and tailored orthopedic management are crucial for children with genetic and metabolic disorders.
  • Awareness of common pitfalls can improve treatment outcomes in this patient population.

Keywords:
Down syndromeEhlers-Danlos syndromeMuscular dystrophyNeurofibromatosisOsteogenesis imperfectaRicketsSkeletal dysplasia

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