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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Renewal of Skin Epidermal Stem Cells01:12

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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Cells of the Epidermis01:24

Cells of the Epidermis

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The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
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Layers of the Epidermis01:21

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The epidermis, the outermost layer of the skin, is composed of several distinct layers. From deep to superficial, the layers of the epidermis are as follows:
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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
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Chemical Peel (Deep, Medium, Light).

Sidney J Starkman1, Devinder S Mangat2

  • 1Facial Plastic Surgeon, Mangat Plastic Surgery, 56 Edwards Village Boulevard, Suite 226, Edwards, CO 81632, USA.

Facial Plastic Surgery Clinics of North America
|November 30, 2019
PubMed
Summary
This summary is machine-generated.

Chemical peeling is a time-tested skin rejuvenation treatment for age-related skin changes like wrinkles and sun damage. This review covers current knowledge and debunks outdated information on chemical peeling efficacy.

Keywords:
Chemical peelChemoexfoliationPhenol-croton oil peelSkin resurfacing

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Area of Science:

  • Dermatology
  • Aesthetic Medicine

Background:

  • Increased life expectancy drives demand for treatments addressing age-related skin conditions.
  • Chemical peeling remains a consistently effective method for skin rejuvenation despite numerous new options.
  • Chemoexfoliation techniques are widely used for rhytids, actinic damage, lentigos, and dyschromias.

Purpose of the Study:

  • To present the latest scientific understanding of chemical peeling.
  • To identify and correct long-held misconceptions regarding chemical peeling procedures.
  • To emphasize the importance of technique and knowledge for successful skin rejuvenation.

Main Methods:

  • Review of current dermatological literature on chemical peeling.
  • Analysis of established and emerging chemoexfoliation protocols.
  • Evaluation of clinical outcomes and patient safety in skin resurfacing.

Main Results:

  • Chemical peeling is a versatile treatment for various dermatological concerns.
  • Outdated information regarding chemical peeling's efficacy and safety has been identified.
  • Proper technique and knowledge are crucial for achieving optimal results.

Conclusions:

  • Chemical peeling is a valuable and enduring treatment option for skin rejuvenation.
  • Adherence to current knowledge and best practices enhances treatment outcomes.
  • Effective chemical peeling requires a combination of expertise and meticulous application.