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Area of Science:

  • Neurology
  • Gastroenterology
  • Immunology

Background:

  • Chorea is a neurological movement disorder with diverse etiologies, including genetic and acquired causes.
  • Coeliac disease is an autoimmune disorder triggered by gluten, typically presenting with gastrointestinal symptoms.
  • Neurological manifestations of coeliac disease are uncommon and often overlooked, especially in the absence of overt GI symptoms.

Observation:

  • A patient presented with rapidly progressive, generalized chorea.
  • The patient lacked typical gastrointestinal symptoms associated with coeliac disease.
  • Diagnostic workup revealed coeliac disease as the underlying cause.

Findings:

  • Coeliac disease can manifest as chorea without gastrointestinal symptoms.
  • A gluten-free diet led to the complete resolution of chorea in this patient.
  • This case highlights the importance of considering coeliac disease in unexplained chorea.

Implications:

  • Early diagnosis of coeliac disease is crucial for managing neurological complications like chorea.
  • A gluten-free diet is an effective treatment for chorea secondary to coeliac disease.
  • This case broadens the understanding of coeliac disease's neurological impact.