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Unilateral Levator Aponeurosis Excision for Marcus Gunn Syndrome and Risk Factors of Residual Jaw Winking
Qingyao Ning1, Jing Cao1, Jiajun Xie1
1Department of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou, Zhejiang, China.
Purpose:
To investigate the association of ptosis, levator, and jaw winking in Marcus Gunn jaw-winking synkinesis (MGJWS), and the risk factor of preservation and outcomes of the unilateral levator excision and frontalis suspension.
Methods:
Clinical features of MGJWS case series from 2011 to 2018 were retrospectively reviewed. Association between jaw winking and ptosis/levator function was statistically analyzed. The patients underwent unilateral levator excision and frontalis suspension using silicone rod or autogenous fascia lata. Clinical outcomes were evaluated in operated patients and the independent risk factors of residual jaw winking were investigated after a long follow-up.
Results:
There were 42 MGJWS patients in 2011 to 2018, accounting for 2.87% of all congenital blepharoptosis. 80% of mild jaw winking was accompanied with mild ptosis and fair levator function, and moderate-to-severe jaw winking was often accompanied with moderate-to-severe ptosis and poor levator function (P < 0.05). Ptosis showed a strong association with excursion of jaw winking (R = 0.785, P < 0.01). Jaw winking was resolved in all 34 operated patients with good correction of ptosis. Severity of jaw winking is an independent risk factor for the residual synkinesis after surgery. Severe preoperative jaw winking had an 18.05 times increased risk of postoperative residual synkinesis compared with moderate jaw winking (P < 0.05).
Conclusions:
In MGJWS eyelid excursion of jaw winking has a direct correlation with ptosis and dysfunction of levator muscle. Unilateral levator aponeurosis excision and frontalis suspension is an efficient approach for MGJWS. Severe jaw winking is a risk factor of residual eyelid synkinesis after surgery.
Insights
Marcus Gunn jaw-winking synkinesis (MGJWS) involves ptosis and levator dysfunction. Unilateral levator excision and frontalis suspension effectively treats MGJWS, though severe jaw winking increases residual synkinesis risk.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Oculoplastics
Background:
- Marcus Gunn jaw-winking synkinesis (MGJWS) is a rare congenital condition.
- It presents with abnormal eyelid movement associated with jaw function.
- Understanding the interplay between ptosis, levator function, and jaw winking is crucial for effective management.
Purpose of the Study:
- To investigate the association between ptosis, levator function, and jaw winking in MGJWS.
- To evaluate the outcomes of unilateral levator excision and frontalis suspension for MGJWS.
- To identify risk factors for residual synkinesis after surgical intervention.
Main Methods:
- Retrospective review of 42 MGJWS cases from 2011-2018.
- Statistical analysis of the correlation between jaw winking severity, ptosis, and levator function.
- Evaluation of surgical outcomes following unilateral levator excision and frontalis suspension (silicone rod or fascia lata).
Main Results:
- A strong positive correlation was found between ptosis severity and jaw winking excursion (R=0.785, P<0.01).
- Mild jaw winking correlated with mild ptosis and fair levator function; severe cases showed moderate-to-severe ptosis and poor levator function (P<0.05).
- All 34 surgically treated patients achieved ptosis correction, but severe preoperative jaw winking significantly increased the risk of residual synkinesis (18.05 times, P<0.05).
Conclusions:
- Eyelid excursion in MGJWS is directly correlated with ptosis and levator muscle dysfunction.
- Unilateral levator aponeurosis excision and frontalis suspension is an effective surgical approach for MGJWS.
- Severe preoperative jaw winking is a significant risk factor for persistent synkinesis post-surgery.
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