Unilateral Levator Aponeurosis Excision for Marcus Gunn Syndrome and Risk Factors of Residual Jaw Winking

Qingyao Ning1, Jing Cao1, Jiajun Xie1

  • 1Department of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou, Zhejiang, China.

Journal of Ophthalmology
|November 30, 2019
PubMed
Abstract

Insights

Marcus Gunn jaw-winking synkinesis (MGJWS) involves ptosis and levator dysfunction. Unilateral levator excision and frontalis suspension effectively treats MGJWS, though severe jaw winking increases residual synkinesis risk.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Oculoplastics

Background:

  • Marcus Gunn jaw-winking synkinesis (MGJWS) is a rare congenital condition.
  • It presents with abnormal eyelid movement associated with jaw function.
  • Understanding the interplay between ptosis, levator function, and jaw winking is crucial for effective management.

Purpose of the Study:

  • To investigate the association between ptosis, levator function, and jaw winking in MGJWS.
  • To evaluate the outcomes of unilateral levator excision and frontalis suspension for MGJWS.
  • To identify risk factors for residual synkinesis after surgical intervention.

Main Methods:

  • Retrospective review of 42 MGJWS cases from 2011-2018.
  • Statistical analysis of the correlation between jaw winking severity, ptosis, and levator function.
  • Evaluation of surgical outcomes following unilateral levator excision and frontalis suspension (silicone rod or fascia lata).

Main Results:

  • A strong positive correlation was found between ptosis severity and jaw winking excursion (R=0.785, P<0.01).
  • Mild jaw winking correlated with mild ptosis and fair levator function; severe cases showed moderate-to-severe ptosis and poor levator function (P<0.05).
  • All 34 surgically treated patients achieved ptosis correction, but severe preoperative jaw winking significantly increased the risk of residual synkinesis (18.05 times, P<0.05).

Conclusions:

  • Eyelid excursion in MGJWS is directly correlated with ptosis and levator muscle dysfunction.
  • Unilateral levator aponeurosis excision and frontalis suspension is an effective surgical approach for MGJWS.
  • Severe preoperative jaw winking is a significant risk factor for persistent synkinesis post-surgery.

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