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Update on Myopia Risk Factors and Microenvironmental Changes
Valeria Coviltir1,2, Miruna Burcel3, Alina Popa Cherecheanu1,4
1Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, Bucharest, Romania.
Abstract:
The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.
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