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Regional assignment of the gene coding for human sucrase-isomaltase (SI) to chromosome 3q25-26
L F West1, M B Davis, F R Green
1MRC Human Biochemical Genetics, Galton Laboratory, University College London.
Annals of Human Genetics
|January 1, 1988
Abstract:
The gene coding for sucrase-isomaltase (SI) has recently been mapped to chromosome 3 using a cDNA probe to analyse DNA from somatic cell hybrids (Green et al. 1987). We have now used this same cDNA probe to obtain a regional localization of this gene. In situ hybridization to normal metaphase chromosomes and to chromosomes from individuals with balanced translocations suggests a regional assignment to chromosome 3q25-26.