Monitoring exercise intensity in diabetes: applicability of "heart rate-index" to estimate oxygen consumption during aerobic and resistance training

Accurate quantification and monitoring of exercise "dose", described by oxygen consumption (VO₂), is necessary for exercise prescription and individualization. However, due to the complexity and elevated cost of direct, gold-standard methods, this is rarely done outside research laboratories. Heart rate-index (HR_index) is a new simple method to estimate VO₂ in healthy and clinical populations. We tested the performance of HR_index to estimate VO₂ in diabetic patients during aerobic (AT) and isotonic training (IT).

Data from 12 males (age: 64 ± 5 years; BMI: 26 ± 12) with type 2 diabetes were analysed. VO₂ and heart rate were measured during one AT and one IT session. Furthermore, VO₂ was indirectly estimated based on HR_index. Then, the correspondence between measured and estimated VO₂ was evaluated by two-way RM-ANOVA, correlation and Bland-Altman analysis.

Estimated average VO₂ values during AT (1292 ± 366 ml/min) were not different from (p = 0.243) and highly correlated with (r = 0.87, p < 0.001) the measured values (1369 ± 417 ml/min), with a small bias and imprecision. Conversely during IT, HR_index overestimated VO₂ compared to the actual measures (1048 ± 404 vs 667 ± 230 ml/min, p ≤ 0.001) and only a moderate correlation was found between values (r = 0.43, p ≤ 0.001), with a large bias and imprecision.

VO₂ of aerobic exercises can be accurately estimated in diabetes patients using HR_index. During isotonic exercise, this method is not recommended for monitoring metabolic intensity due to large overestimation and imprecision. In aerobic exercise, HR_index offers a simple and valid alternative to the direct VO₂ determination and may favour the applicability of time-resolved measures of exercise "dose".