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Updated: Jan 2, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
How to do it: value-driven sharp recanalization of central vein occlusion
Gary Sem Wye Yoong1, Frederick Hong Xiang Koh2, Bernard Boon Kee Wee1
1Interventional Radiology, National University Health System, Singapore.
Central vein occlusions pose risks for haemodialysis patients and may resist standard treatments. Sharp recanalization offers a safe, cost-effective solution for these challenging blockages.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Nephrology
Background:
- Patients undergoing haemodialysis are prone to central vein occlusions.
- These occlusions can lead to severe clinical issues.
- Conventional treatments may not always be effective.
Observation:
- Conventional revascularization techniques using guidewire and catheter may be ineffective for resistant central vein occlusions.
- Sharp recanalization presents a novel approach for managing these complex vascular lesions.
Findings:
- Value-driven sharp recanalization is demonstrated as a safe and cost-effective treatment option.
- This technique provides a viable solution for patients with refractory central vein occlusions.
Implications:
- Sharp recanalization can improve treatment outcomes for haemodialysis patients with central vein occlusions.
- This approach may reduce the need for more invasive procedures and associated healthcare costs.
- Further research should explore long-term efficacy and patient selection criteria for sharp recanalization.
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