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Updated: Jan 2, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

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Long-term follow-up in high risk hypertensive patients with carotid dolicoarteriopathies

Antonio Valvano1, Giorgio Bosso1, Valentina Apuzzi1

  • 1Department of Translational Medical Sciences, Federico II University, Naples, Italy.

International Angiology : a Journal of the International Union of Angiology
|November 30, 2019
PubMed

Insights

Carotid dolicoarteriopathies (CDA) are common but do not increase the risk of cerebrovascular events like stroke or TIA in hypertensive patients. This study found no significant association between CDA and major cerebral events in high-risk individuals.

Area of Science:

  • Vascular Neurology
  • Cerebrovascular Diseases
  • Medical Imaging

Background:

  • Carotid dolicoarteriopathies (CDA) are frequently observed but their link to cerebrovascular diseases remains uncertain.
  • Understanding the clinical significance of CDA is crucial for managing patients at risk.

Purpose of the Study:

  • To investigate the potential relationship between carotid dolicoarteriopathies and the incidence of cerebrovascular events.
  • To clarify if CDA is an independent risk factor for stroke or transient ischemic attack.

Main Methods:

  • Retrospective analysis of 2124 hypertensive patients with high cardiovascular risk.
  • Carotid ultrasound performed between January 2000 and December 2008.
  • 10-year follow-up data collected on cerebrovascular events (stroke and TIA).

Main Results:

  • Prevalence of CDA was 12.9% (274/2124), with higher frequency in females and left carotid artery.
  • Cerebrovascular event rates were similar in patients with and without CDA (10.94% vs. 10.97%).
  • No significant differences observed in stroke (8.39% vs. 8.38%) or TIA (2.55% vs. 2.59%) rates.

Conclusions:

  • Carotid dolicoarteriopathies are not associated with an increased occurrence of cerebrovascular events.
  • CDA does not appear to be a significant risk factor for stroke or TIA in this high-risk hypertensive population.
Abstract

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