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The Association Between Keratoconus and Mitral Valve Prolapse: A Meta-Analysis

Juan A Siordia1, Jimena C Franco2

  • 1Department of Internal Medicine, Banner University Medical Center - South Campus, 2800 E Ajo Way, Tucson, AZ 85713, United States.

Current Cardiology Reviews
|November 30, 2019
PubMed
Abstract

Insights

This meta-analysis found a significant association between Keratoconus (KC) and Mitral Valve Prolapse (MVP). Patients with KC are more likely to have MVP, and vice versa, indicating a co-existing prevalence.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Medical Genetics

Background:

  • The association between Keratoconus (KC) and Mitral Valve Prolapse (MVP) is debated.
  • Previous cross-sectional studies have yielded indeterminate results regarding their co-existing prevalence.

Conclusions:

  • There is a statistically significant co-existing prevalence between MVP and KC.
  • Patients with KC have a higher likelihood of presenting with MVP.
  • Patients with MVP have a higher likelihood of presenting with KC.
Keywords:
Keratoconusassociationcardiologyepidemiologymitral valve prolapseophthalmology.

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