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Knee Arthrocentesis in Adults
Published on: February 25, 2022
Osteoarticular infections in pediatrics
Paula Andrade Alvares1, Marcelo Jenné Mimica2
1Santa Casa de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Insights
Pediatric osteoarticular infections, including osteomyelitis and septic arthritis, require prompt diagnosis and treatment. Early antimicrobial therapy and surgical intervention when needed improve outcomes for children.
Area of Science:
- Pediatric Infectious Diseases
- Musculoskeletal Infections
- Microbiology
Background:
- Osteoarticular infections remain a significant cause of pediatric morbidity.
- Staphylococcus aureus is the primary pathogen, with increasing detection of Kingella kingae, particularly via molecular methods.
Purpose of the Study:
- To synthesize current information on pediatric osteoarticular infections.
- To review epidemiological and microbiological profiles, diagnostic approaches, and treatment strategies.
Main Methods:
- Non-systematic review of literature from PubMed, SciELO, LILACS, and Google Scholar (last 10 years).
- Keywords included: "bone and joint infection", "children", "pediatric", "osteomyelitis", "septic arthritis", "spondylodiscitis".
Main Results:
- Microbiological identification guides treatment; inflammatory markers aid follow-up.
- Imaging is crucial for initial diagnosis; empirical treatment should consider age, clinical status, and local resistance patterns.
- Surgical intervention may be necessary for diagnosis, source control, and function preservation. Acute complications include sepsis; late complications can cause developmental deformities.
Conclusions:
- Early and accurate diagnosis is paramount for optimal prognosis.
- Prompt, appropriate antimicrobial therapy and timely surgical intervention, when indicated, are critical for better patient outcomes.
Objective:
To collect the most up-to-date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment.
Source Of Data:
A non-systematic review was performed on the search engines PubMed, SciELO, LILACS, and Google Scholar, using the keywords "bone and joint infection", "children", "pediatric", "osteomyelitis", "septic arthritis" and "spondylodiscitis" over the last ten years. The most relevant articles were selected by the authors to constitute the database.
Synthesis Of Data:
Osteoarticular infections are still a major cause of morbidity in pediatrics. Their main etiology is Staphylococcus aureus, but there has been an increase in the detection of Kingella kingae, especially through molecular methods. Microbiological identification allows treatment direction, while evidence of inflammatory activity assists in treatment follow-up. Imaging tests are especially useful in the initial diagnosis of infections. Empirical treatment should include coverage for the main microorganisms according to the age and clinical conditions of the patient, while considering the local resistance profile. Surgical procedures can be indicated for diagnosis, focus control, and function preservation. Acute complications include sepsis, deep venous thrombosis, and pulmonary embolism. Deaths are rare. Late complications are uncommon but may lead to deformities that compromise motor development.
Conclusion:
A correct and early diagnosis, prompt implementation of adequate antimicrobial therapy, and focus control, when indicated, are critical to a better prognosis.
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