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Multiple paraspinal intramuscular myxomas: case report.

Joseph S Domino1, Shane Weindel2, Sarah Woodrow1

  • 1Departments of1Neurosurgery and.

Journal of Neurosurgery. Spine
|November 30, 2019
PubMed
Summary

Multiple paraspinal myxomas, a rare benign tumor, were identified in a patient, representing the first reported case. Surgical excision is recommended for symptomatic relief, as malignant transformation is not documented.

Keywords:
Mazabraud syndromeMcCune-Albright syndromeintramuscular myxomaoncologyparaspinal mass

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Intramuscular myxomas (IMMs) are rare benign mesenchymal tumors typically found in large skeletal muscles.
  • Paraspinal IMMs are uncommon but can cause neurological deficits due to mass effect, necessitating inclusion in differential diagnoses for paraspinal masses.

Observation:

  • A 52-year-old male presented with multiple paraspinal tumors showing concerning growth on serial imaging.
  • This case represents the first documented instance of multiple paraspinal intramuscular myxomas.

Findings:

  • CT-guided biopsy and surgical excision confirmed the largest mass as an intramuscular myxoma.
  • Histopathological analysis confirmed the diagnosis of intramuscular myxoma.

Implications:

  • Multiple IMMs may indicate an underlying genetic syndrome (e.g., Mazabraud, McCune-Albright, Carney complex).
  • Despite variable presentations and genetic associations, malignant transformation of IMMs into myxoid sarcoma has not been reported.
  • Surgical intervention should be considered for symptomatic relief in patients with multiple paraspinal myxomas.