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Related Experiment Video

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Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
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Bioactive Glass Applications in Dentistry.

Hans Erling Skallevold1, Dinesh Rokaya2,3, Zohaib Khurshid4

  • 1Faculty of Dentistry, University of Oslo, 0455 Oslo, Norway.

International Journal of Molecular Sciences
|December 1, 2019
PubMed
Summary
This summary is machine-generated.

Bioactive glasses (BAG) are advanced biomaterials promoting tissue regeneration by stimulating the body's natural healing processes. This review highlights their diverse and promising applications in dental and medical hard and soft tissue engineering.

Keywords:
antimicrobialbioactive glassdentistrytissue regeneration

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Biotechnology

Background:

  • Current research in biomaterials focuses on oral hard and soft tissue engineering using bioactive ingredients.
  • Bioactive glasses (BAG) are key materials that activate immune cells and proteins, promoting natural tissue regeneration.
  • These materials facilitate the growth of natural ground substance, tissue components, and long-lasting tissues.

Purpose of the Study:

  • To provide an overview of the current and promising applications of bioactive glasses specifically within dentistry.
  • To explore the potential of bioactive glasses in various dental procedures and treatments.

Main Methods:

  • Literature review of existing studies on bioactive glasses.
  • Analysis of research focusing on the application of bioactive glasses in dental and medical fields.
  • Synthesis of information on the mechanisms and outcomes of bioactive glass usage.

Main Results:

  • Bioactive glasses exhibit significant potential for hard tissue regeneration in both medicine and dentistry.
  • Specific dental applications include use as restorative materials, mineralizing agents, implant coatings, and in pulp capping, root canal treatments, and air-abrasion.
  • Beyond dentistry, bioactive glasses are utilized in orthopedics and soft tissue restoration.

Conclusions:

  • Bioactive glasses are versatile biomaterials with a wide range of established and emerging applications in dentistry.
  • Their bioactive properties support tissue regeneration, making them valuable for numerous clinical dental interventions.
  • The review underscores the importance and potential of bioactive glasses in advancing dental biomaterials and therapies.