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Related Experiment Videos

Cancer treatment protocols. Who gets chosen?

J S Goodwin1, W C Hunt, C G Humble

  • 1Department of Medicine, Medical College of Wisconsin, Milwaukee 53226.

Archives of Internal Medicine
|October 1, 1988
PubMed
Summary
This summary is machine-generated.

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Elderly cancer patients are underrepresented in clinical trials. Only 7% of participants were over 70, compared to 31% of all cancer patients, hindering the development of optimal cancer therapies for older adults.

Area of Science:

  • Oncology
  • Geriatric Medicine
  • Clinical Trial Design

Background:

  • Clinical trials are crucial for advancing cancer treatment.
  • The aging population presents unique challenges in cancer care.
  • Representation of diverse age groups in trials is essential for generalizable results.

Purpose of the Study:

  • To compare the age distribution of adult cancer patients in New Mexico with those enrolled in Southwest Oncology Group (SWOG) protocols.
  • To identify potential underrepresentation of elderly patients in cancer clinical trials.

Main Methods:

  • Retrospective analysis of cancer incidence data in New Mexico (1959-1982).
  • Comparison with patient data from SWOG-sponsored cancer treatment protocols in New Mexico during the same period.
Keywords:
Biomedical and Behavioral ResearchEmpirical ApproachSouthwest Oncology Group

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  • Age-specific demographic analysis.

    • Main Results:

    • Elderly patients (over 70 years) constituted 31% of all adult cancer cases in New Mexico.
    • Only 7% of adult cancer patients enrolled in SWOG protocols were over 70 years.
    • Significant underrepresentation of elderly individuals in SWOG cancer treatment protocols was observed across all cancer sites.

    Conclusions:

    • Elderly patients are substantially underrepresented in SWOG cancer treatment protocols.
    • This underrepresentation may impede the development of effective and tailored cancer therapies for the geriatric population.
    • Further efforts are needed to ensure equitable inclusion of older adults in clinical research.