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Published on: April 11, 2025
A PRESing case of visual changes and confusion
Tanisha Ronnie1, Larrisa Beyerlein2, Michael Murati3
1University of Minnesota School of Medicine, 420 Delaware Street SE, Minneapolis, MN 55455, United States.
Insights
Posterior reversible encephalopathy syndrome (PRES) can cause vision loss in children with systemic lupus erythematosus (SLE). Early diagnosis and treatment of PRES are crucial for preventing permanent neurological damage and other severe outcomes.
Area of Science:
- Pediatric Neurology
- Ophthalmology
- Nephrology
Background:
- Visual disturbances are rare in children, often benign.
- Certain medical conditions like Systemic Lupus Erythematosus (SLE), autoimmune disorders, transplant recipients, renal disease, and eclampsia warrant careful evaluation for visual complaints.
- Children with underlying conditions require closer scrutiny for vision abnormalities.
Abstract:
Visual disturbances are an uncommon pediatric chief complaint. Usually, after a complete ocular exam including visual acuity, most causes are benign and not life-threatening. Children with abnormal visual complaints who have underlying medical conditions, such as SLE or other autoimmune conditions, a recipient of a transplant, renal disease, and even eclampsia require closer scrutiny. We report a 10-year-old female with a history of systemic lupus erythematosus complicated by hypertension and cardiomyopathy secondary to lupus who presented to the emergency department with a history of vision loss and headache. Head computer tomography demonstrated findings of posterior reversible encephalopathy syndrome (PRES). PRES is a clinical disease associated with cranial radiological findings of heterogenous etiologies that is often reversible. Prompt recognition and treatment are important in preventing permanent damage, long term morbidity and even death.
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