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A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

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[Postnatal outcome from polyhydramnios without sonographic abnormalities].

C Bertholdt¹, A-L Fijean², O Morel¹

¹Service d'obstétrique et de médecine fœtale, maternité régionale du CHRU de Nancy, 10, rue du Dr Heydenreich, 54000 Nancy, France; IADI, Inserm U1254, rue du Morvan, 54500 Vandoeuvre-lès-Nancy, France.

Gynecologie, Obstetrique, Fertilite & Senologie

|December 1, 2019

Summary

This summary is machine-generated.

Polyhydramnios without malformations can lead to adverse outcomes, including death or postnatal complications. Maternal obesity, early diagnosis, and severe polyhydramnios are significant risk factors.

Keywords:

Diagnostic prénatal Hydramnios Issue périnatale Morbidité postnatale Perinatal outcome Polyhydramnios Postnatal morbidity Prenatal diagnosis Prenatal ultrasound screening Échographie prénatale

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Area of Science:

Obstetrics and Gynecology
Perinatology

Background:

Polyhydramnios, an excess of amniotic fluid, can complicate singleton pregnancies.
Assessing adverse outcomes in polyhydramnios without morphological abnormalities is crucial for risk stratification.

Purpose of the Study:

To evaluate the adverse outcomes associated with polyhydramnios in the absence of morphological abnormalities.
To identify maternal, obstetrical, and polyhydramnios characteristics linked to adverse pregnancy outcomes.

Main Methods:

A retrospective observational cohort study was conducted in a French tertiary care unit from 2008 to 2018.
Included were women with singleton pregnancies complicated by polyhydramnios, excluding those with morphological abnormalities.
Adverse outcomes were defined as a composite of death, postnatal malformation, or chronic pathology.

Main Results:

The overall adverse outcome rate was 24.2% in 91 women.
Maternal obesity, early diagnosis (before 32 weeks gestation), and severe polyhydramnios were significantly associated with adverse outcomes.
The postnatal mortality rate was 5.5%, and 11% of malformations were diagnosed postnatally.

Conclusions:

Polyhydramnios without apparent morphological abnormalities carries a significant risk of adverse outcomes.
Second-line ultrasound, including assessment for isolated maternal diabetes, is recommended.
Consideration for systematic genetic assessment may be warranted in select cases.