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Updated: Jan 2, 2026

Author Spotlight: Oxygen-Independent Assays to Measure Mitochondrial Function in Mammals
Published on: May 19, 2023
Every Breath You Take: New Insights into Plant and Animal Oxygen Sensing
Daniel J Gibbs1, Michael J Holdsworth2
1School of Biosciences, University of Birmingham, Edgbaston, B15 2TT, UK.
Abstract:
Responses to hypoxia are regulated by oxygen-dependent degradation of kingdom-specific proteins in animals and plants. Masson et al. (2019) identified and characterized the mammalian counterpart of an oxygen-sensing pathway previously only observed in plants. Alongside other recent findings identifying novel oxygen sensors, this provides new insights into oxygen-sensing origins and mechanisms in eukaryotes.
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