Related Experiment Video
Updated: Jan 2, 2026

Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives
Published on: April 10, 2017
Sample stabilization strategies: a case study review of unique sample collection and handling procedures
Corey Ohnmacht1, Megan Cooley1, Ryan Darling1
1Bioanalytical Laboratory, PRA Health Sciences, 10836 Strang Line Road, Lenexa, KA 66221, USA.
Abstract:
The ability to maintain analyte stability is crucial in order to obtain accurate and meaningful data. Stability should be evaluated in a manner that the entire lifecycle of the sample is taken into account, that is, from the moment the sample is collected from the patient until the last analysis is complete. Evaluation of the sample collection and handling procedure is thus necessary in order to prevent analyte instability potentially encountered downstream in the analytical process. This manuscript details cases of analyte instability attributed to factors such as enzymatic degradation, matrix composition, analytical technique and oxidation to name a few. As well each case describes a unique collection and handling procedure that was necessary to achieve stability prior to analysis.
Related Concept Videos
Sample Handling
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
Sampling Methods: Sample Types
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
Sampling Methods: Overview
In analytical chemistry, the choice of...
Sample Preparation for Analysis: Overview
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Convenience Sampling Method
Convenience sampling is a non-random method of sample selection; this method selects individuals that are easily accessible and may result in biased data. For example, a marketing...

