Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Plant Tissue Culture02:57

Plant Tissue Culture

40.0K
Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
40.0K
Microbial Growth Measurement: Indirect Methods01:27

Microbial Growth Measurement: Indirect Methods

1.2K
Estimating microbial growth is essential for understanding population dynamics and environmental adaptations. Indirect methods provide valuable insights by measuring parameters such as turbidity, metabolic activity, and biomass, enabling efficient and reproducible assessments.During exponential growth, microbial cells scatter light proportionally to their biomass, a principle used in turbidity measurements. About one million cells per milliliter produce detectable scattering, which a...
1.2K
Cell Culture01:21

Cell Culture

21.7K
Most vertebrate cells grow in vitro attached to a substrate as a monolayer, called adherent cultures. The flasks and plates used to grow cells are chemically treated to facilitate cell attachment. However, a few cell types, such as hematopoietic cells, can grow in a suspension. In contrast to adherent cultures, suspension cultures can grow in non-treated cultureware using magnetic stirrers or spinner flasks to agitate the culture media
21.7K
Nature and Nurture01:10

Nature and Nurture

22.1K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
22.1K
Meristems and Plant Growth02:36

Meristems and Plant Growth

48.8K
Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
48.8K
Microbial Growth Media01:27

Microbial Growth Media

1.2K
Microbial growth media are essential tools in microbiology, providing the nutrients and conditions necessary to cultivate and study microorganisms. These media are categorized by their composition, consistency, and functional roles, enabling researchers to investigate microbial physiology, behavior, and interactions.Types and Consistencies of Growth MediaGrowth media can be solid, liquid, or semisolid. Solid media, often agar-based, allow visible colony growth for isolation and enumeration.
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Project Extension For Community Health Care Outcomes Improves Provider Confidence and Behaviors in Gender-Affirming Care for Youth.

Transgender health·2025
Same author

Gender-affirming care in adolescents and young adults with cardiovascular conditions: clinical considerations in a limited evidence landscape.

Cardiology in the young·2025
Same author

Online learning modules improve confidence in providing gender affirming care for youth.

BMC medical education·2024
Same author

Clinical Care of Acne Vulgaris for Transgender and Gender Diverse Youth.

Pediatrics in review·2024
Same author

Evaluation and medical care of intersex and gender diverse youth.

Pediatric radiology·2024
Same author

Gender-Diverse Youth with Turner Syndrome: Special Management Considerations.

JCEM case reports·2024
Same journal

EDITORIAL INTRODUCTION.

Current opinion in endocrinology, diabetes, and obesity·2026
Same journal

Exploring the role of parathyroid hormone in sarcopenia: A review.

Current opinion in endocrinology, diabetes, and obesity·2026
Same journal

Normocalcemic primary hyperparathyroidism: an update on diagnostic and management challenges.

Current opinion in endocrinology, diabetes, and obesity·2026
Same journal

Prediabetes before pregnancy: implications for risk stratification and research.

Current opinion in endocrinology, diabetes, and obesity·2026
Same journal

Secondary hyperparathyroidism in chronic kidney disease: update on pathophysiology and new treatment targets.

Current opinion in endocrinology, diabetes, and obesity·2026
Same journal

Revisiting the relationship between weight loss and bone health in people living with obesity: insights from the latest evidence.

Current opinion in endocrinology, diabetes, and obesity·2026
See all related articles

Related Experiment Video

Updated: Jan 2, 2026

Enhancement of the Initial Growth Rate of Agricultural Plants by Using Static Magnetic Fields
05:17

Enhancement of the Initial Growth Rate of Agricultural Plants by Using Static Magnetic Fields

Published on: July 8, 2016

13.7K

Update on methods to enhance growth.

Juanita K Hodax1, Sara A DiVall

  • 1Division of Pediatric Endocrinology, University of Washington and Seattle Children's Hospital, Seattle, Washington, USA.

Current Opinion in Endocrinology, Diabetes, and Obesity
|December 3, 2019
PubMed
Summary
This summary is machine-generated.

Recombinant human growth hormone (rhGH) effectively treats short stature in children. New data suggest rhGH is safe for isolated growth hormone deficiency, while recombinant C-type natriuretic peptide shows promise for achondroplasia.

More Related Videos

Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids
11:01

Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids

Published on: September 25, 2016

8.1K
Robotic Sensing and Stimuli Provision for Guided Plant Growth
08:02

Robotic Sensing and Stimuli Provision for Guided Plant Growth

Published on: July 1, 2019

8.4K

Related Experiment Videos

Last Updated: Jan 2, 2026

Enhancement of the Initial Growth Rate of Agricultural Plants by Using Static Magnetic Fields
05:17

Enhancement of the Initial Growth Rate of Agricultural Plants by Using Static Magnetic Fields

Published on: July 8, 2016

13.7K
Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids
11:01

Nutrient Regulation by Continuous Feeding for Large-scale Expansion of Mammalian Cells in Spheroids

Published on: September 25, 2016

8.1K
Robotic Sensing and Stimuli Provision for Guided Plant Growth
08:02

Robotic Sensing and Stimuli Provision for Guided Plant Growth

Published on: July 1, 2019

8.4K

Area of Science:

  • Pediatric Endocrinology
  • Growth Hormone Therapy
  • Skeletal Dysplasias

Background:

  • Short stature in children is a significant concern.
  • Various medical interventions aim to enhance growth and final adult height.

Purpose of the Study:

  • To review current treatments for pediatric short stature.
  • To discuss recent findings on the efficacy and safety of growth-enhancing therapies.

Main Methods:

  • Review of recent clinical data and cohort studies.
  • Analysis of treatment outcomes for recombinant human growth hormone (rhGH), insulin-like growth factor 1, and emerging therapies.

Main Results:

  • rhGH efficacy is confirmed for growth hormone deficiency (GHD) and idiopathic short stature.
  • Long-term malignancy risk with rhGH appears low for isolated GHD, but warrants caution in other diagnoses.
  • Recombinant human insulin-like growth factor 1 is effective for pregnancy-associated plasma protein A2 deficiency.
  • Delaying puberty with GnRH agonists or aromatase inhibitors is controversial but may augment height when combined with rhGH.
  • Recombinant C-type natriuretic peptide (CNP) shows safety and increased growth velocity in achondroplasia over 42 months.

Conclusions:

  • rhGH remains a cornerstone therapy for pediatric short stature with confirmed efficacy and safety profiles.
  • Combined therapies, such as growth-promoting agents with rhGH, may offer greater height augmentation.
  • Recombinant CNP presents a promising therapeutic option for short stature in achondroplasia.