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A pilot study of forearm microvascular impairment and pain while using a telephone
Jeanne Hersant1, Pierre Ramondou2, Celine Guilleron3
1Vascular Medicine, University Hospital Center, Angers, France.
Objective:
To determine if using a telephone can induce forearm pain and ischemia.
Design:
Prospective case-control trial.
Setting:
Vascular laboratory in the university hospital in Angers between September 2018 and March 2019.
Participants:
Fifteen apparently healthy subjects (controls) and 32 patients with suspected thoracic outlet syndrome (TOS) of vascular or non-vascular origin.
Intervention:
Hand-holding a cellular phone to answer a call from investigators.
Main Outcome Measures:
Presence of forearm fatigue or pain (primary outcome), ability to hold the phone with each hand for 1 min (secondary outcome 1) and decrease in forearm transcutaneous oxygen pressure DROP index indicating forearm ischemia (secondary outcome 2). A DROP < -15 mm Hg defined ischemia.
Results:
Answering a phone call resulted in 25(78%) patients with forearm fatigue or pain and in 18 (56%) cases in the inability to hold the phone for 1 min, on one or both arms in patients with suspected TOS, but never occurred in healthy volunteers (p < .05 and p < .001). The presence of ischemia was observed in one or both arms in 10 (31%) patients with proved TOS and was always associated to phone-induced pain. Three (20%) of the controls had phone-induced ischemia. All had asymptomatic TOS and remained asymptomatic during the phone test (p = .42 from suspected-TOS patients).
Conclusion:
The phone conversation resulted in pain in many patients with suspected TOS. Transcutaneous oximetry can document the underlying ischemia. Forearm phone-call-induced pain may be indicative of TOS provided that no earplug or headset is used. Trial registrationClinicalTrials.govNCT03355274.
