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Published on: November 9, 2019
Addiction severity modulates the precuneus involvement in internet gaming disorder: Functionality, morphology and
Guang-Heng Dong1, Min Wang2, Ziliang Wang3
1Center for Cognition and Brain Disorders, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang Province, China; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, Zhejiang Province, China.
Addiction severity in internet gaming disorder (IGD) is linked to precuneus brain activity, volume, and connectivity. Higher severity correlates with increased precuneus activation and volume during cue exposure.
Area of Science:
- Neuroscience
- Psychiatry
- Addiction Research
Background:
- The precuneus shows variable activation in addiction studies during cue exposure.
- Understanding precuneus involvement in internet gaming disorder (IGD) is crucial.
Purpose of the Study:
- To investigate the relationship between IGD severity and precuneus involvement.
- To examine functional, morphological, and connectivity aspects of the precuneus in relation to IGD severity.
Main Methods:
- Recruited 65 subjects with IGD.
- Collected brain responses during a gaming cue-craving task.
- Assessed brain structure, precuneus volume, and connectivity.
Main Results:
- IGD severity positively correlated with precuneus activation during cue exposure.
- IGD severity positively correlated with precuneus volume and hippocampal gyrus to precuneus connectivity.
- IGD severity negatively correlated with middle frontal gyrus to precuneus connectivity.
Conclusions:
- In IGD, severity is associated with precuneus functionality, morphology, and connectivity.
- The precuneus may integrate executive control information with craving signals.
- Findings highlight the precuneus's role in the neurobiology of internet gaming disorder.
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