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Related Experiment Video

Updated: Jan 2, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Radiological findings in ischaemic cholangiopathy.

F Alabdulghani1, G M Healy1, C P Cantwell1

  • 1Radiology Department and University College Dublin, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

Clinical Radiology
|December 4, 2019
PubMed
Summary

Ischaemic cholangiopathy, caused by poor bile duct blood flow, can lead to serious complications and graft failure after liver transplants. This review covers its pathology, imaging, and interventional radiology management.

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Area of Science:

  • Vascular Surgery
  • Hepatobiliary Surgery
  • Interventional Radiology

Background:

  • Ischaemic cholangiopathy results from compromised arterial blood supply to the bile duct.
  • This condition can cause bile duct necrosis, leakage, biloma, and sepsis.
  • It is a significant factor in graft loss following orthotopic liver transplantation.

Purpose of the Study:

  • To review the pathology and radiological features of ischaemic cholangiopathy.
  • To outline the management strategies for ischaemic cholangiopathy, emphasizing interventional radiology.

Main Methods:

  • Literature review focusing on pathology, radiology, and interventional management of ischaemic cholangiopathy.
  • Analysis of causes including vasculitis and complications of endovascular procedures in native livers.

Main Results:

  • Ischaemic cholangiopathy presents with specific pathological and imaging findings.
  • Interventional radiology offers therapeutic options for managing this condition.

Conclusions:

  • Understanding the pathology and radiological signs is crucial for diagnosing ischaemic cholangiopathy.
  • Interventional radiology plays a key role in managing ischaemic cholangiopathy, particularly in post-transplant settings.