Location-Dependent B-cell Function in Glioblastoma

Ferdinando Pucci1

  • 1School of Medicine, Oregon Health and Science University, Portland, Oregon. pucci@ohsu.edu.

Immunotherapy has shown remarkable successes in several tumor types and is now the first-line treatment for several conditions, including recurring disease. Nonetheless, a large fraction of patients does not respond, which is particularly true in glioblastoma. The results of Lee-Chang and colleagues point to intratumoral B cells as a potential target for immunotherapy.See article by Lee-Chang et al., p. 1928.

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