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[Disorders of spatial working memory in affective disorders with mild current depression and their neurophysiological
S A Galkin1, A G Peshkovskaya1, G G Simutkin1
1Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Science, Tomsk, Russia.
Aim:
To assess spatial working memory disorders in patients with mild depressive disorders and determine their neurophysiological correlates.
Material And Methods:
Thirty patients (right-handed) with ICD-10 diagnosis Mood Disorders (F31.3, F32.0, F33.0, F34.1), aged 37±8 years, were examined before treatment. A control group included 30 mentally and somatically healthy individuals (32±7 years old). The study of spatial working memory was carried out using the Corsi Block-Tapping test. EEG was recorded and the values of the spectral power of theta, alpha and beta rhythms were analyzed.
Results And Conclusion:
A decrease in the level of working memory that was correlated with higher values of theta rhythm power in the frontal and occipital regions and alpha rhythm in the frontal cortex was observed in affective disorders with mild depressive symptoms.
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