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How Many Subpopulations Is Too Many? Exponential Lower Bounds for Inferring Population Histories
Younhun Kim1, Frederic Koehler1, Ankur Moitra1,2
1Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Abstract:
Reconstruction of population histories is a central problem in population genetics. Existing coalescent-based methods, such as the seminal work of Li and Durbin, attempt to solve this problem using sequence data but have no rigorous guarantees. Determining the amount of data needed to
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