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Related Experiment Video

Updated: Jan 2, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Published on: May 27, 2021

Treatment options for tic disorders.

Renata Rizzo¹, Mariangela Gulisano¹

¹Child and Adolescent Psychiatry Section, Department of Clinical and Experimental Medicine, Catania University, Catania, Italy.

Expert Review of Neurotherapeutics

|December 5, 2019

Summary

This summary is machine-generated.

Managing tics in Gilles de la Tourette syndrome (GTS) requires a personalized approach. Clinicians should assess tic impact, consider comorbidities, and discuss treatment duration and side effects with patients and families.

Keywords:

Alpha-2 agonists Tourette syndrome antipsychotics tics vesicular monoamine transporter-2 inhibitors

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Area of Science:

Neurology
Neurodevelopmental Disorders
Clinical Management

Background:

Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder characterized by motor and phonic tics.
Treatment of GTS, particularly tics, presents significant challenges for clinicians.
GTS often co-occurs with psychiatric disorders, complicating management.

Purpose of the Study:

To outline a structured approach for clinicians managing tics in patients with GTS.
To emphasize the importance of individualized treatment strategies for GTS.
To review key considerations in the pharmacological management of GTS tics.

Main Methods:

Review of current clinical practices and expert opinion on GTS tic management.
Focus on a step-by-step approach to treatment initiation and patient counseling.
Consideration of patient-specific factors, including tic severity, comorbidities, and tolerance.

Main Results:

Treatment should prioritize assessing the impact of tics on the patient's quality of life.
Comorbidities must be evaluated before initiating tic-suppressing treatments.
Informed consent includes discussing treatment duration, onset of action, and potential side effects.

Conclusions:

A multidisciplinary and individualized approach is crucial for effective GTS tic management.
Patient and family education regarding treatment expectations and risks is paramount.
Treatment selection should align with individual patient tolerance and symptom profile.