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Atheroembolic Renal Disease: A Case Series
K S Jansi Prema1, Anila A Kurien1
1Renopath, Center for Renal and Urological Pathology, Chennai, Tamil Nadu, India.
Insights
Atheroembolic renal disease (AERD) is often underdiagnosed. Renal biopsy is crucial for diagnosing AERD, a condition caused by cholesterol emboli blocking kidney arteries.
Area of Science:
- Nephrology
- Cardiovascular Pathology
Background:
- Atheroembolic renal disease (AERD) is a manifestation of systemic cholesterol embolization syndrome.
- It results from cholesterol crystal emboli lodging in renal arteries, originating from ulcerated atherosclerotic plaques.
- Kidney involvement is frequent due to the abdominal aorta's proximity and the kidneys' high blood flow.
Abstract:
Atheroembolic renal disease (AERD), a part of systemic cholesterol embolization syndrome, is caused by the occlusion of small arteries in the kidneys by cholesterol crystal emboli from ulcerated atherosclerotic plaques. Kidney is commonly involved because of its proximity to the abdominal aorta and its enormous blood supply. AERD is an under diagnosed condition. We report eight cases of AERD, highlighting the variability in its clinical presentation and the importance of a renal biopsy to arrive at a definitive diagnosis.
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