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Helicobacter pylori Infection in Children: a Comprehensive Review
1Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran.
Insights
Helicobacter pylori infection is a global health issue, particularly in developing nations. Risk factors include family crowding and socioeconomic status, with potential links to anemia and ITP.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Public Health
Background:
- Helicobacter pylori infection is a prevalent global health concern with diverse gastrointestinal and extra-intestinal manifestations.
- Higher prevalence rates are observed in developing countries, influenced by factors like family size and socioeconomic status.
- The infection is linked to specific conditions, including iron-deficiency anemia, vitamin B12 deficiency, and acute idiopathic thrombocytopenic purpura (ITP).
Abstract:
Helicobacter pylori infection is a worldwide health problem, presenting with gastrointestinal (GI) or extra GI symptoms. The infection is more common in developing than developed countries. Crowded families, paternal education level, and socioeconomic status are among the risk factors of H. pylori infection. The infection is associated with some diseases such as iron-deficiency anemia, B12 deficiency, acute idiopathic thrombocytopenic purpura (ITP). Invasive and non-invasive tests could be used for diagnosis, while the gold standard is a biopsy specimen of GI tract. Nodular gastritis is the most common finding of childhood H. pylori infection. Based on the susceptibility profile and compliance, different treatment options could be applied.
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