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Related Experiment Videos

Clinical multi-functional OCT for retinal imaging.

Shinnosuke Azuma1,2, Shuichi Makita1,2, Deepa Kasaragod1,2

  • 1Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.

Biomedical Optics Express
|December 5, 2019
PubMed
Summary
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A new compact Jones-matrix optical coherence tomography (JM-OCT) device provides multi-functional imaging for the human eye. This technology enables non-invasive investigation of abnormal tissues like those found in age-related macular degeneration.

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Medical Imaging

Background:

  • Optical Coherence Tomography (OCT) is a key imaging modality in ophthalmology.
  • Current OCT devices can be bulky and limited in functionality.
  • Investigating the posterior human eye requires advanced, non-invasive techniques.

Purpose of the Study:

  • To develop a compact, multi-functional OCT device for posterior eye imaging.
  • To integrate multiple imaging capabilities into a single, portable unit.
  • To demonstrate the utility of the device for clinical applications.

Main Methods:

  • Development of a compact Jones-matrix OCT (JM-OCT) device.
  • Integration of all optical and electronic components into a single package.

Related Experiment Videos

  • Acquisition of scattering intensity, OCT angiography, and degree of polarization uniformity images.

    • Main Results:

    • A compact, multi-functional JM-OCT prototype was successfully developed.
    • The device achieved integrated imaging of scattering intensity, OCT angiography, and polarization uniformity.
    • Local birefringence measurements were demonstrated.
    • Multi-functional imaging of eyes with age-related macular degeneration was performed.

    Conclusions:

    • The compact JM-OCT device offers versatile, non-invasive imaging of the posterior human eye.
    • This technology is valuable for in vivo investigation of ocular tissues and diseases.
    • The integrated functionalities enhance diagnostic capabilities for conditions like AMD.