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Related Experiment Videos

Ungual Tuberculosis: A Unique Clinical Case.

Ana Cristina da Silva Sousa1, Manuel Sousa2, David Tente3

  • 1Dermatology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

Skin Appendage Disorders
|December 5, 2019
PubMed
Summary
This summary is machine-generated.

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Cutaneous tuberculosis (TB) is rare, especially affecting the nail apparatus. This case highlights TB as a cause of persistent finger infection, emphasizing its diagnostic challenge in such presentations.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Cutaneous tuberculosis (TB) is uncommon, with nail apparatus involvement being exceptionally rare and typically secondary.
  • Primary exogenous cutaneous TB presenting as a nail infection is exceedingly rare.

Observation:

  • A 76-year-old female presented with a year-long history of onychodystrophy and purulent drainage of her left index finger, unresponsive to antibiotics and antifungals.
  • Physical examination revealed paronychia and onychodystrophy. Biopsy showed epithelioid granulomas with necrosis, and cultures confirmed *Mycobacterium tuberculosis* complex.
  • Imaging excluded pulmonary TB but revealed dactylitis of the distal phalanx.

Findings:

  • The patient was diagnosed with primary cutaneous tuberculosis of the nail apparatus.
Keywords:
Cutaneous tuberculosisNail diseaseOnychodystrophyParonychia

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  • Histopathology and microbiological cultures confirmed *Mycobacterium tuberculosis* complex infection.
  • Successful treatment with a standard anti-TB regimen led to complete lesion resolution.

    • Implications:

    • Cutaneous TB, particularly affecting the nail apparatus, presents a diagnostic challenge.
    • Painless paronychia with refractory purulent drainage and onychodystrophy should raise suspicion for cutaneous TB.
    • Early diagnosis and appropriate anti-TB therapy are crucial for favorable outcomes in rare cutaneous TB cases.