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C-lection by the DM15 Motif Gets LARP1 to the TOP

Mark A Bayfield1, Kyra Kerkhofs1, Farnaz Mansouri-Noori1

  • 1Department of Biology, York University, Toronto, ON, Canada.

Structure (London, England : 1993)
|December 5, 2019
PubMed

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Directing Proteins to the Rough Endoplasmic Reticulum01:34

Directing Proteins to the Rough Endoplasmic Reticulum

The organelle-specific signaling sequences direct proteins synthesized in the cytosol to their final destination like ER, mitochondria, peroxisomes, etc. Some of the proteins directed to ER are then trafficked via vesicles to other organelles within the cell or the extracellular environment through the Golgi complex. For example, the rough ER synthesizes soluble proteins for transportation to the lysosomes or secretion out of the cell. It can also synthesize transmembrane proteins that can...
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