Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Altered peripheral nerve conduction in HIV-patients.

P Y Chavanet1, M Giroud, J P Lancon

  • 1Department of Infectious and Tropical Diseases, University Hospital of Dijon, France.

Cancer Detection and Prevention
|January 1, 1988
PubMed
Summary

Peripheral nerve conduction studies reveal subclinical neuropathy in 28% of HIV-seropositive patients. Early detection of this myelinic or axonal neuropathy may warrant prompt treatment, even in asymptomatic individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unraveling the care pathway for CAR T-cell therapy in large B-cell lymphoma: insights from a nationwide study in France (2018-2023).

Leukemia & lymphoma·2026
Same author

French early nationwide idecabtagene vicleucel chimeric antigen receptor T-cell therapy experience in patients with relapsed/refractory multiple myeloma (FENIX): A real-world IFM study from the DESCAR-T registry.

British journal of haematology·2024
Same author

First case of proven invasive pulmonary infection due to Trichoderma longibrachiatum in a neutropenic patient with acute leukemia.

Journal de mycologie medicale·2018
Same author

[Retrospective study of 25 cases of pulmonary mucormycosis in acute leukaemia].

Revue des maladies respiratoires·2018
Same author

Impact of pharmaceutical intervention on quality of life and coping strategies in patients with haematological malignancies.

Annales pharmaceutiques francaises·2016
Same author

[Evaluation of the efficacy of aflibercept's in the treatment of neovascular age-related macular degeneration in treatment-naive and switched patients. Report of 86 cases].

Journal francais d'ophtalmologie·2016

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Clinical Electrophysiology

Background:

  • Human Immunodeficiency Virus (HIV) infection can affect the nervous system.
  • Peripheral neuropathies are a known complication, but their early presentation is less understood.

Purpose of the Study:

  • To investigate subclinical peripheral nerve abnormalities in HIV-seropositive individuals without overt neurological symptoms.
  • To characterize the type and distribution of any detected neuropathies.

Main Methods:

  • Electrophysiological assessment of peripheral nerve conduction was conducted.
  • The study included 28 HIV-seropositive patients with no clinical signs of neurological impairment.

Main Results:

Related Experiment Videos

  • Subclinical neuropathy was identified in 8 out of 28 patients (28%).
  • The neuropathy observed was predominantly distal and could be either myelinic or axonal in nature.

    • Conclusions:

    • A significant proportion of asymptomatic HIV-seropositive patients exhibit electrophysiological evidence of peripheral neuropathy.
    • These early, subclinical nerve involvements suggest a potential benefit from initiating treatment even before clinical manifestation.