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HAART Induced Gynaecomastia
Mahesh Dave1, Lavanya Sr2, Manoj Patidar3
1Professor Medicine.
The Journal of the Association of Physicians of India
|December 6, 2019
Summary
Gynaecomastia, a benign breast enlargement in males, can be drug-induced. This case highlights a rare instance of gynaecomastia linked to the highly active antiretroviral therapy (HAART) regimen known as TLE.
Area of Science:
- Endocrinology
- Pharmacology
- Infectious Diseases
Background:
- Gynaecomastia is benign glandular enlargement of the male breast.
- Numerous medications are known to cause gynaecomastia.
- The highly active antiretroviral therapy (HAART) regimen, TLE, is rarely associated with this condition.
Observation:
- A 42-year-old male, diagnosed as HIV-positive for 10 years, was initiated on the TLE regimen.
- The patient subsequently developed gynaecomastia over an 11-month period.
Findings:
- This case report documents a rare instance of gynaecomastia in an HIV-positive patient receiving HAART.
- The TLE regimen is implicated as a potential cause of drug-induced gynaecomastia.
Implications:
- Clinicians should consider TLE as a potential cause of gynaecomastia in HIV-positive patients.
- Further research may be warranted to elucidate the mechanism of TLE-induced gynaecomastia.
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