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Concomitant atopic dermatitis and psoriasis - a retrospective review
Kelly Barry1, Pedro Zancanaro2, Rachel Casseres1
1Tufts University School of Medicine, Boston, MA, USA.
The Journal of Dermatological Treatment
|December 6, 2019
Summary
Patients with both atopic dermatitis (AD) and psoriasis often have hand involvement and may need multiple systemic therapies. Consider AD in psoriasis patients with difficult-to-treat hand conditions.
Area of Science:
- Dermatology
- Immunology
- Clinical Medicine
Background:
- Atopic dermatitis (AD) and psoriasis, once viewed as distinct, can now be recognized as co-occurring conditions.
- Limited data exists for patients presenting with both AD and psoriasis.
- This study aims to characterize this patient cohort and their therapeutic responses.
Purpose of the Study:
- To define the characteristics of patients diagnosed with both atopic dermatitis and psoriasis.
- To summarize the treatment responses in patients with coexisting AD and psoriasis.
Main Methods:
- Retrospective chart review conducted at Tufts Medical Center Department of Dermatology.
- Data collected from January 1, 2012, to May 1, 2019.
- Included patients with psoriasis (n=1390), AD (n=912), and both AD and psoriasis (n=30).
Main Results:
- The prevalence of concomitant AD and psoriasis was 1.5%.
- High prevalence of hand involvement (63%) observed in patients with both conditions.
- Systemic therapy was utilized in 73% of patients; biologics were often insufficient, with 30% needing sequential and 22% needing simultaneous biologics.
Conclusions:
- Patients with overlapping AD and psoriasis exhibit significant hand involvement and a poor response to topical treatments.
- Multiple systemic agents are frequently required for effective management.
- Atopic dermatitis should be considered in psoriasis patients with recalcitrant hand disease.
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